CUSTOM ITEM: Semi-Prep Guard Column Cartridges, Diamond Hydride, Replacement Cartridges, 10 mm ID x 10 mm Long, 4 um, 100 A. Cogent TYPE-C Brand. 3/PK.
Additional Info:
Semi‑Prep Diamond Hydride™ Guard Cartridges for Column Protection and Method Longevity
The 70000‑SP‑G1 Diamond Hydride™ Semi‑Prep Guard Column Cartridges are custom‑manufactured replacement cartridges designed to protect Diamond Hydride™ semi‑preparative analytical columns from particulate contamination, strongly retained matrix components, and irreversible fouling. Built on Cogent TYPE‑C™ silica hydride technology, these guard cartridges preserve chromatographic performance while extending the usable life of valuable semi‑prep columns.
Configured in a 10 mm ID × 10 mm length format with 4 µm, 100 Å Diamond Hydride stationary phase, these cartridges provide highly effective upstream protection without altering method selectivity or retention behavior.
Why Semi‑Prep Guard Columns Are Essential
Semi‑preparative HILIC methods often involve:
Higher sample loads
Complex or less‑filtered matrices
Repeated injections during purification campaigns
The use of a matched Diamond Hydride™ guard cartridge helps:
Capture particulates and strongly retained contaminants before they reach the main column
Maintain consistent retention and peak shape over extended use
Reduce downtime and replacement costs for semi‑prep columns
Improve reproducibility in repeated injections and fraction collection workflows
By sacrificially retaining contaminants, the guard cartridge serves as the first line of defense in demanding semi‑prep environments.
Diamond Hydride™ Stationary Phase Consistency
These guard cartridges are packed with the same Diamond Hydride™ stationary phase chemistry as the corresponding semi‑prep columns, ensuring:
No change in selectivity or elution order
Minimal added dead volume
Seamless method transfer from guard to column
Stable retention mechanisms under high‑organic HILIC conditions
The silica hydride surface also supports mixed‑mode interactions, making these guards effective for a wide range of polar analytes.
Intended Applications
70000‑SP‑G1 guard cartridges are routinely used to protect and with Diamond Hydride™ semi‑prep columns for:
Purification of polar small molecules
Peptide and metabolite isolation
Preparative‑scale method development
Repeated injection workflows where column protection is critical
They are particularly valuable when working with samples that cannot be fully cleaned prior to injection.
Replacement Cartridge Format
Dimensions: 10 mm ID × 10 mm length
Particle Size: 4 µm
Pore Size: 100 Å
Packaging: 3 cartridges per pack
Cartridges are intended to be replaced regularly based on sample cleanliness, pressure increase, or changes in chromatographic performance.
Custom Item Notice (Prep Columns and Guards)
This product is classified as a Custom Item. As with all Diamond Hydride™ semi‑prep columns and guard cartridges, this item can be made to order, is non‑returnable.